Publications

  1. S. Meier*, R. Stark*, M. Frentsch, and A. Thiel A. 2008. The influence of different stimulation conditions on the assessment of antigen-induced CD154 expression on CD4+ T cells. *equal contribution. Cytometry A. 73(11):1035-1042.
  2. J. Dong, C. Ivascu, H. D. Chang, P. Wu, R. Angeli, L. Maggi, F. Eckhardt, L. Tykocinski, C. Haefliger, B. Möwes, J. Sieper, A. Radbruch, F. Annunziato, and A. Thiel. 2007. IL-10 is excluded from the functional cytokine memory of human CD4+ memory T lymphocytes. J Immunol. 179(4):2389-2396.
  3. Frentsch M, Arbach O, Kirchhoff D, Moewes B, Worm M, Rothe M, Scheffold A, Thiel A. 2005. Direct access to CD4+ T cells specific for defined antigens according to CD154 expression. Nat Med. 11(10):1118-24.
  4. Kohler S, Wagner U, Pierer M, Kimmig S, Oppmann B, Möwes B, Jülke K, Romagnani C, Thiel A. 2005. Post-thymic in vivo proliferation of naive CD4+ T cells constrains the TCR repertoire in healthy human adults. Eur J Immunol. 35(6):1987-94.
  5. U. Baron, S. Floess, G. Wieczorek, K. Baumann, A. Grutzkau, J. Dong, A. Thiel, T.J. Boeld, P. Hoffmann, M. Edinger, I. Turbachova, A. Hamann, S. Olek, and J. Huehn. 2007. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. Eur J Immunol. 37(9):2378-2389.
  6. D. Kirchhoff, M. Frentsch, P. Leclerk, D. Bumann, S. Rausch, S. Hartmann, A. Thiel and A. Scheffold. 2007. Identification and isolation of murine antigen-reactive T cells according to CD154 expression. Eur J Immunol. 37(9):2370-2377.
  7. T. Alexander*, A. Thiel*, O. Rosen, G. Massenkeil, A. Sattler. S. Kohler. H. Mei, H.  Radtke, E. Gromnica-Ihle, G. R. Burmester. R. Arnold, A. Radbruch, and F. Hiepe. 2009. Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system. Blood. 113(1):214-223. *equal contribution.
  8. C. Ivascu, R. Wasserkort, R. Lesche, J. Dong, H. Stein, A. Thiel, and F. Eckhardt. 2007. DNA methylation profiling of transcription factor genes in normal lymphocyte development and lymphomas. Int J Biochem Cell Biol. 39(7-8):1523-1538.
  9. N. Babel, G. Brestrich, L. P. Gondek, A. Sattler, M. W. Wlodarski, N. Poliak, N. Bethke, A. Thiel, M. H. Hammer, P. Reinke, and J. P. Maciejewski. 2009. Clonotype analysis of cytomegalovirus-specific cytotoxic T lymphocytes. J Am Soc Nephrol. 20(2):344-52.
  10. S. Kohler, and A. Thiel. 2009. Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. Blood. 113(4):769-774.
  11. A. Sattler, U. Wagner, M. Rossol, J. Sieper, P. Wu, A. Krause, W. A. Schmidt, S. Radmer, S. Kohler, C. Romagnani, and A. Thiel A. 2009. Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation. Blood. 113(9):1948-1956.

Patents

Schönbrunn A., Frentsch M. and A. Thiel - DRFZ
„Verfahren zum Nachweiss und zur Isolierung von regulatorischen T-Lymphozyten, die ein definiertes Antigen erkennen“
European Patent (2007)
PCT Patent (2007)

Frentsch M., Muller D.R., Schönbrunn A., Kohler S. and A. Thiel - Miltenyi Biotec GmbH
„Verfahren zum Nachweis und Entfernung von konventionellen nicht regulatorischen T- Lymphozyten aus einem Gemisch mit regulatorischen T-Zellen“
European Patent (2009)